The dog filarial nematode, also known as Dirofilaria immitis, is a parasitic worm that causes heartworm disease in dogs.
It is transmitted to the animals through the bite of infected mosquitoes. The adult worms reside in the heart and blood vessels, causing serious damage to the cardiac and respiratory systems over time. Early detection and treatment are crucial, as the disease can be fatal if left untreated. Preventative measures consist in providing monthly preventative medication and reducing exposure to mosquitoes.
The search of novel control methods is a central aspect of Animal Health research and a challenge that Invenesis is now committed in.
Recently, we have been keen to propose three model species of filariae: the dog heartworm D. immitis, and the rodent filarial nematodes Litosomoides sigmodontis and Acanthocheilonema viteae, for which certain stages of development are accessible for research campaigns on potential candidate treatments.